Maria Plug heeft scheikunde gestudeerd en is gepromoveerd in de moleculaire biologie aan de Universiteit Leiden. Vanaf 1992 werkte zij 10 jaar als moleculair biologisch onderzoeker in Duitsland. Terug in Nederland maakte zij de overstap naar het onderwijs.
Maria Plug is manager van Centrum Bioscience en Diagnostiek van hogeschool Leiden, waar zij nascholingen voor laboratoriummedewerkers organiseert.
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